Medicine without signs.

Fever without Localizing Signs

The list of microbes that cause fever in children is extensive. Relative importance of specific agents varies with age, season, and associated symptoms. The focus of this chapter is the febrile child with occult bacterial infection. Table 14-1 shows the most common causes of serious bacterial infection in children younger than 3 months. The division at 1 month is not absolute; considerable over...

Symptoms and Signs in Clinical Medicine

Nuclear medicine UK: signs of progress

At last there are clear signs that a road ahead is being mapped. Recent National Institute of Clinical Excellence guidelines recommend a major development for nuclear medicine in cardiology. The present abysmal UK rate of 1.1 investigations/1 000 000/year compared poorly with the known EU rate of 4/1 000 000/year and the inflated rate of 7/1 000 000/year achieved in the USA. National Institute ...

Clinical signs in medicine: pulsus paradoxus.

Historical Aspects The reduction in pulse volume during inspiration was first described by Lomer in 1669 in constrictive pericarditis1. A similar finding was described by Floyer and later by William in 1850 in bronchial asthma1. Adolf Kussmaul (Freiberg, Germany) coined the term “pulsus paradoxus” in 1873 in three patients with constrictive pericarditis. The “paradox” was: (1) the discrepancy b...

Marked aortic regurgitation without peripheral vascular signs.